Paper $27.50 ISBN: 9780226629186 Will Publish May 2019
Cloth $82.50 ISBN: 9780226629049 Will Publish May 2019
An e-book edition will be published.

Synthesizing Hope

Matter, Knowledge, and Place in South African Drug Discovery

Anne Pollock

Synthesizing Hope

Anne Pollock

208 pages | 7 halftones | 6 x 9 | © 2019
Paper $27.50 ISBN: 9780226629186 Will Publish May 2019
Cloth $82.50 ISBN: 9780226629049 Will Publish May 2019
E-book $27.50 ISBN: 9780226629216 Will Publish May 2019
Synthesizing Hope opens up the material and social world of pharmaceuticals by focusing on an unexpected place: iThemba Pharmaceuticals. Founded in 2009 with a name taken from the Zulu word for hope, the small South African startup with an elite international scientific board was tasked with drug discovery for tuberculosis, HIV, and malaria. Anne Pollock uses this company as an entry point for exploring how the location of the scientific knowledge production matters, not only for the raw materials, production, licensing, and distribution of pharmaceuticals but also for the making of basic scientific knowledge.

Consideration of this case exposes the limitations of global health frameworks that implicitly posit rich countries as the only sites of knowledge production. Analysis of iThemba identifies the problems inherent in global north/south divides at the same time as it highlights what is at stake in who makes knowledge and where. It also provides a concrete example for consideration of the contexts and practices of postcolonial science, its constraints, and its promise.

Synthesizing Hope explores the many legacies that create conditions of possibility for South African drug discovery, especially the specific form of settler colonialism characterized by apartheid and resource extraction. Paying attention to the infrastructures and laboratory processes of drug discovery underscores the materiality of pharmaceuticals from the perspective of their makers, and tracing the intellectual and material infrastructures of South African drug discovery contributes new insights about larger social, political, and economic orders.
Introduction / Hope in South African Drug Discovery

One / Questioning the Bifurcations in Global Health Discourses
Two / In the Shadows of the Dynamite Factory
Three / Science for a Post-apartheid South Africa
Four / “African Solutions for African Problems”
Five / Im/materiality of Pharmaceutical Knowledge Making
Six / Hope in Flow

Epilogue / The Afterlives of Hope

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